Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
E0Z10_g2157Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (419 aa)    
Predicted Functional Partners:
E0Z10_g7390
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 0.978
E0Z10_g816
Uncharacterized protein.
  
 0.958
E0Z10_g7812
Uncharacterized protein.
  
 0.957
E0Z10_g6430
MaoC-like domain-containing protein.
  
 0.951
E0Z10_g8505
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.948
E0Z10_g8113
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.948
E0Z10_g5768
WD_REPEATS_REGION domain-containing protein.
    
 0.938
E0Z10_g651
Uncharacterized protein.
  
 0.915
E0Z10_g4521
Pyruvate carboxyltransferase domain-containing protein.
  
 
 0.911
E0Z10_g5567
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.903
Your Current Organism:
Xylaria hypoxylon
NCBI taxonomy Id: 37992
Other names: X. hypoxylon
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