STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E0Z10_g6634Uncharacterized protein. (409 aa)    
Predicted Functional Partners:
E0Z10_g6441
Uncharacterized protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.564
E0Z10_g9755
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
    
  0.529
E0Z10_g5200
Uncharacterized protein; Belongs to the peptidase S8 family.
    
  0.529
E0Z10_g906
Protein kinase domain-containing protein.
    
 0.510
E0Z10_g4545
Uncharacterized protein.
    
 0.507
E0Z10_g7998
Histone H2B; Belongs to the histone H2B family.
    
  0.494
E0Z10_g9198
Uncharacterized protein.
    
 0.480
E0Z10_g3477
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
 0.480
E0Z10_g748
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
    
 0.480
E0Z10_g1018
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
    
  0.478
Your Current Organism:
Xylaria hypoxylon
NCBI taxonomy Id: 37992
Other names: X. hypoxylon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.