Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
E0Z10_g2032Uncharacterized protein. (440 aa)    
Predicted Functional Partners:
E0Z10_g4715
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
   
 0.970
E0Z10_g5909
RRM domain-containing protein.
    
 0.969
E0Z10_g8879
Uncharacterized protein.
   
 
 0.960
E0Z10_g9216
Uncharacterized protein.
    
 
 0.954
E0Z10_g7755
Nuclear cap-binding protein subunit 2.
    
 0.948
E0Z10_g766
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
    
 
 0.940
E0Z10_g7596
Uncharacterized protein.
   
 
 0.935
E0Z10_g7481
Uncharacterized protein.
    
 
 0.932
E0Z10_g9430
Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
   
 0.929
E0Z10_g774
Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family.
   
 0.924
Your Current Organism:
Xylaria hypoxylon
NCBI taxonomy Id: 37992
Other names: X. hypoxylon
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