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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E0Z10_g9472Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1454 aa)    
Predicted Functional Partners:
E0Z10_g3417
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.902
E0Z10_g1643
Uncharacterized protein.
    
 0.853
E0Z10_g2642
Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
     
 0.833
E0Z10_g8578
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.810
E0Z10_g1937
Uncharacterized protein.
    
 
 0.579
E0Z10_g7162
FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]
    
   0.573
E0Z10_g2300
Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.
    
   0.569
E0Z10_g585
HECT domain-containing protein.
      
 0.528
E0Z10_g3529
Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
      
 0.465
E0Z10_g1511
Uncharacterized protein.
    
 
 0.453
Your Current Organism:
Xylaria hypoxylon
NCBI taxonomy Id: 37992
Other names: X. hypoxylon
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