STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E0Z10_g5448Autophagy-related protein 3. (346 aa)    
Predicted Functional Partners:
E0Z10_g6655
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
  
 
 0.999
E0Z10_g8901
Autophagy-related protein.
  
 0.997
E0Z10_g8792
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.
    
 0.996
E0Z10_g4502
Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
   
 0.990
E0Z10_g4106
Zn(2)-C6 fungal-type domain-containing protein.
   
 0.982
E0Z10_g10107
ATG16 domain-containing protein.
   
 0.973
E0Z10_g3458
Protein kinase domain-containing protein.
   
 
 0.963
E0Z10_g1530
Uncharacterized protein.
   
 0.959
E0Z10_g5222
Lipase_3 domain-containing protein.
   
 
 0.959
E0Z10_g906
Protein kinase domain-containing protein.
   
 
 0.952
Your Current Organism:
Xylaria hypoxylon
NCBI taxonomy Id: 37992
Other names: X. hypoxylon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.