STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E0Z10_g7651AB hydrolase-1 domain-containing protein. (676 aa)    
Predicted Functional Partners:
E0Z10_g585
HECT domain-containing protein.
   
 
 0.768
E0Z10_g1389
Ubiquitin-like domain-containing protein.
    
 0.740
E0Z10_g6452
Ubiquitin-like domain-containing protein.
   
 0.620
E0Z10_g10088
Ubiquitin-like domain-containing protein.
   
 0.620
E0Z10_g7397
Uncharacterized protein.
   
 0.620
E0Z10_g6262
Uncharacterized protein.
   
   0.608
E0Z10_g6655
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
    
 0.606
E0Z10_g1895
UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family.
    
 0.529
E0Z10_g2880
E2_bind domain-containing protein.
    
 0.526
E0Z10_g1785
Uncharacterized protein.
   
 0.523
Your Current Organism:
Xylaria hypoxylon
NCBI taxonomy Id: 37992
Other names: X. hypoxylon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.