STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
egtAGlutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. (413 aa)    
Predicted Functional Partners:
SDL62926.1
L-histidine Nalpha-methyltransferase.
 
  
 0.738
SDL02100.1
Cysteine synthase A.
  
  
  0.719
SDL68611.1
4-amino-4-deoxychorismate lyase.
  
  
  0.717
SDK78451.1
N-succinyldiaminopimelate aminotransferase.
  
  
  0.710
SDL73403.1
Cystathione beta-lyase.
     
 0.683
ilvE
Branched-chain amino acid aminotransferase, group I; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
  
  0.552
SDK62453.1
Para-nitrobenzyl esterase; Belongs to the type-B carboxylesterase/lipase family.
       0.500
SDL19316.1
Hypothetical protein.
  
     0.486
SDK62487.1
Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase.
       0.469
SDK68419.1
Hypothetical protein.
  
     0.458
Your Current Organism:
Glycomyces sambucus
NCBI taxonomy Id: 380244
Other names: CGMCC 4.3147, DSM 45047, G. sambucus, Glycomyces sambucus Gu et al. 2007, Glycomyces sp. E71, JCM 15472, strain E71
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