STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDK68184.1Fructuronate reductase; Belongs to the mannitol dehydrogenase family. (453 aa)    
Predicted Functional Partners:
SDK68217.1
Glucuronate isomerase.
 
 
 0.993
SDK55815.1
Mannonate dehydratase.
 
  
 0.916
SDK80272.1
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
   
 
 0.849
xylA
Xylose isomerase; Belongs to the xylose isomerase family.
    
 0.842
pfp
Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
 0.840
SDL03146.1
UDPglucose 6-dehydrogenase.
     
 0.835
SDL00972.1
Mannose-6-phosphate isomerase, type 1.
     
 0.827
SDK68199.1
L-fuconate dehydratase; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
    
 0.825
SDK89351.1
Mannose-6-phosphate isomerase.
     
 0.819
SDK68162.1
Predicted dehydrogenase.
       0.773
Your Current Organism:
Glycomyces sambucus
NCBI taxonomy Id: 380244
Other names: CGMCC 4.3147, DSM 45047, G. sambucus, Glycomyces sambucus Gu et al. 2007, Glycomyces sp. E71, JCM 15472, strain E71
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.