STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDL00972.1Mannose-6-phosphate isomerase, type 1. (382 aa)    
Predicted Functional Partners:
SDL00904.1
Phosphomannomutase.
  
 
 0.969
SDL00954.1
Phospho-glucose isomerase C-terminal SIS domain-containing protein.
  
 
 0.957
SDL25701.1
Glucose-6-phosphate isomerase.
  
 
 0.919
SDL23835.1
Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
 
  
 0.871
SDL03612.1
Phosphomannomutase.
  
 
 0.868
SDK80272.1
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
    
 0.834
pfp
Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
     
 0.827
SDK68184.1
Fructuronate reductase; Belongs to the mannitol dehydrogenase family.
     
 0.827
glmS
Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.827
SDK67950.1
Glutamine--fructose-6-phosphate transaminase.
    
  0.818
Your Current Organism:
Glycomyces sambucus
NCBI taxonomy Id: 380244
Other names: CGMCC 4.3147, DSM 45047, G. sambucus, Glycomyces sambucus Gu et al. 2007, Glycomyces sp. E71, JCM 15472, strain E71
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