SDL66326.1 protein (Glycomyces sambucus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

SDL66326.1

D-alanyl-D-alanine carboxypeptidase. (197 aa)

Predicted Functional Partners:

SDL66371.1

0.890

SDL66344.1

0.829

SDK61855.1

0.646

SDK68515.1

0.646

SDL68414.1

0.646

SDL66304.1

0.538

SDL82399.1

0.444

SDL06155.1

0.437

SDL24735.1

0.437

SDL01090.1

0.435

Your Current Organism:

Glycomyces sambucus

NCBI taxonomy Id: 380244
Other names: CGMCC 4.3147, DSM 45047, G. sambucus, Glycomyces sambucus Gu et al. 2007, Glycomyces sp. E71, JCM 15472, strain E71

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDK61855.1	SDL06155.1	SAMN05216298_0821	SAMN05216298_2527	Hypothetical protein.	Cell elongation-specific peptidoglycan D,D-transpeptidase.	0.657
SDK61855.1	SDL24735.1	SAMN05216298_0821	SAMN05216298_3259	Hypothetical protein.	Peptidoglycan synthetase FtsI.	0.617
SDK61855.1	SDL66326.1	SAMN05216298_0821	SAMN05216298_4693	Hypothetical protein.	D-alanyl-D-alanine carboxypeptidase.	0.646
SDK68515.1	SDL06155.1	SAMN05216298_1163	SAMN05216298_2527	Membrane carboxypeptidase (penicillin-binding protein).	Cell elongation-specific peptidoglycan D,D-transpeptidase.	0.836
SDK68515.1	SDL24735.1	SAMN05216298_1163	SAMN05216298_3259	Membrane carboxypeptidase (penicillin-binding protein).	Peptidoglycan synthetase FtsI.	0.836
SDK68515.1	SDL66326.1	SAMN05216298_1163	SAMN05216298_4693	Membrane carboxypeptidase (penicillin-binding protein).	D-alanyl-D-alanine carboxypeptidase.	0.646
SDL01090.1	SDL66326.1	SAMN05216298_2258	SAMN05216298_4693	Protein of unknown function.	D-alanyl-D-alanine carboxypeptidase.	0.435
SDL06155.1	SDK61855.1	SAMN05216298_2527	SAMN05216298_0821	Cell elongation-specific peptidoglycan D,D-transpeptidase.	Hypothetical protein.	0.657
SDL06155.1	SDK68515.1	SAMN05216298_2527	SAMN05216298_1163	Cell elongation-specific peptidoglycan D,D-transpeptidase.	Membrane carboxypeptidase (penicillin-binding protein).	0.836
SDL06155.1	SDL24735.1	SAMN05216298_2527	SAMN05216298_3259	Cell elongation-specific peptidoglycan D,D-transpeptidase.	Peptidoglycan synthetase FtsI.	0.889
SDL06155.1	SDL66326.1	SAMN05216298_2527	SAMN05216298_4693	Cell elongation-specific peptidoglycan D,D-transpeptidase.	D-alanyl-D-alanine carboxypeptidase.	0.437
SDL06155.1	SDL68414.1	SAMN05216298_2527	SAMN05216298_4789	Cell elongation-specific peptidoglycan D,D-transpeptidase.	Membrane carboxypeptidase (penicillin-binding protein).	0.823
SDL24735.1	SDK61855.1	SAMN05216298_3259	SAMN05216298_0821	Peptidoglycan synthetase FtsI.	Hypothetical protein.	0.617
SDL24735.1	SDK68515.1	SAMN05216298_3259	SAMN05216298_1163	Peptidoglycan synthetase FtsI.	Membrane carboxypeptidase (penicillin-binding protein).	0.836
SDL24735.1	SDL06155.1	SAMN05216298_3259	SAMN05216298_2527	Peptidoglycan synthetase FtsI.	Cell elongation-specific peptidoglycan D,D-transpeptidase.	0.889
SDL24735.1	SDL66326.1	SAMN05216298_3259	SAMN05216298_4693	Peptidoglycan synthetase FtsI.	D-alanyl-D-alanine carboxypeptidase.	0.437
SDL24735.1	SDL68414.1	SAMN05216298_3259	SAMN05216298_4789	Peptidoglycan synthetase FtsI.	Membrane carboxypeptidase (penicillin-binding protein).	0.821
SDL66304.1	SDL66326.1	SAMN05216298_4692	SAMN05216298_4693	ADP-ribosyltransferase exoenzyme.	D-alanyl-D-alanine carboxypeptidase.	0.538
SDL66326.1	SDK61855.1	SAMN05216298_4693	SAMN05216298_0821	D-alanyl-D-alanine carboxypeptidase.	Hypothetical protein.	0.646
SDL66326.1	SDK68515.1	SAMN05216298_4693	SAMN05216298_1163	D-alanyl-D-alanine carboxypeptidase.	Membrane carboxypeptidase (penicillin-binding protein).	0.646

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Network Stats

number of nodes:

11

number of edges:

25

average node degree:

4.55

avg. local clustering coefficient:

0.852

expected number of edges:

17

PPI enrichment p-value:

0.053

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006351

Transcription, DNA-templated

4 of 40

1.53

0.99

0.0070

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003899

DNA-directed 5-3 RNA polymerase activity

3 of 7

2.16

1.45

0.0017

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000428

DNA-directed RNA polymerase complex

3 of 7

2.16

1.85

0.00026

GO:0032991

Protein-containing complex

4 of 202

0.82

0.47

0.0363

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:286

RNA polymerase, and Transcription antitermination

3 of 5

2.3

1.62

0.00088

CL:153

Structural constituent of ribosome, and Elongation factor

4 of 72

1.27

0.73

0.0197

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03020

RNA polymerase

3 of 4

2.4

2.16

8.26e-05

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000428

DNA-directed RNA polymerase complex

4 of 64

1.32

0.88

0.0079

GOCC:0032991

Protein-containing complex

6 of 439

0.66

0.39

0.0403

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0240

DNA-directed RNA polymerase

3 of 5

2.3

1.92

0.00023

KW-0548

Nucleotidyltransferase

3 of 36

1.45

0.81

0.0181

KW-0804

Transcription

4 of 123

1.04

0.6

0.0260

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