STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDL70402.1Pentapeptide repeat-containing protein. (220 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.962
SDL37758.1
AAA ATPase domain-containing protein; Manually curated.
  
  
  0.693
SDL70387.1
Arginase; Belongs to the arginase family.
       0.596
SDL70449.1
Transglycosylase SLT domain-containing protein.
   
   0.545
SDK57019.1
Pyruvate kinase; Manually curated; Belongs to the pyruvate kinase family.
    
  0.514
SDL03776.1
Protein of unknown function.
  
  
 0.499
SDL38185.1
Protein of unknown function.
  
  
 0.499
SDL58929.1
Choice-of-anchor A domain-containing protein.
  
     0.465
SDL70312.1
Hypothetical protein.
    
   0.463
SDL70423.1
EF-hand domain pair.
       0.427
Your Current Organism:
Glycomyces sambucus
NCBI taxonomy Id: 380244
Other names: CGMCC 4.3147, DSM 45047, G. sambucus, Glycomyces sambucus Gu et al. 2007, Glycomyces sp. E71, JCM 15472, strain E71
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.