node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
XALC_0249 | XALC_0250 | XALC_0249 | XALC_0250 | Hypothetical protein; Belongs to the MtfA family. | Putative secreted protein. | 0.570 |
XALC_0249 | XALC_0253 | XALC_0249 | XALC_0253 | Hypothetical protein; Belongs to the MtfA family. | Hypothetical protein. | 0.458 |
XALC_0249 | birA | XALC_0249 | XALC_0251 | Hypothetical protein; Belongs to the MtfA family. | Probable biotin--[acetyl-coa-carboxylase] ligase protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.502 |
XALC_0249 | coaX | XALC_0249 | XALC_0252 | Hypothetical protein; Belongs to the MtfA family. | Putative transcriptional regulator, bvg accessory factor family transcription regulator protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.432 |
XALC_0250 | XALC_0249 | XALC_0250 | XALC_0249 | Putative secreted protein. | Hypothetical protein; Belongs to the MtfA family. | 0.570 |
XALC_0250 | XALC_0253 | XALC_0250 | XALC_0253 | Putative secreted protein. | Hypothetical protein. | 0.521 |
XALC_0250 | birA | XALC_0250 | XALC_0251 | Putative secreted protein. | Probable biotin--[acetyl-coa-carboxylase] ligase protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.581 |
XALC_0250 | coaX | XALC_0250 | XALC_0252 | Putative secreted protein. | Putative transcriptional regulator, bvg accessory factor family transcription regulator protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.532 |
XALC_0253 | XALC_0249 | XALC_0253 | XALC_0249 | Hypothetical protein. | Hypothetical protein; Belongs to the MtfA family. | 0.458 |
XALC_0253 | XALC_0250 | XALC_0253 | XALC_0250 | Hypothetical protein. | Putative secreted protein. | 0.521 |
XALC_0253 | birA | XALC_0253 | XALC_0251 | Hypothetical protein. | Probable biotin--[acetyl-coa-carboxylase] ligase protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.805 |
XALC_0253 | coaX | XALC_0253 | XALC_0252 | Hypothetical protein. | Putative transcriptional regulator, bvg accessory factor family transcription regulator protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.780 |
birA | XALC_0249 | XALC_0251 | XALC_0249 | Probable biotin--[acetyl-coa-carboxylase] ligase protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Hypothetical protein; Belongs to the MtfA family. | 0.502 |
birA | XALC_0250 | XALC_0251 | XALC_0250 | Probable biotin--[acetyl-coa-carboxylase] ligase protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Putative secreted protein. | 0.581 |
birA | XALC_0253 | XALC_0251 | XALC_0253 | Probable biotin--[acetyl-coa-carboxylase] ligase protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Hypothetical protein. | 0.805 |
birA | coaBC | XALC_0251 | XALC_0373 | Probable biotin--[acetyl-coa-carboxylase] ligase protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.494 |
birA | coaX | XALC_0251 | XALC_0252 | Probable biotin--[acetyl-coa-carboxylase] ligase protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Putative transcriptional regulator, bvg accessory factor family transcription regulator protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.976 |
birA | panC | XALC_0251 | XALC_1206 | Probable biotin--[acetyl-coa-carboxylase] ligase protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Probable pantoate--beta-alanine ligase protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.678 |
birA | panD | XALC_0251 | XALC_1207 | Probable biotin--[acetyl-coa-carboxylase] ligase protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Probable aspartate 1-decarboxylase precursor (aspartate alpha-decarboxylase) protein; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.624 |
coaBC | birA | XALC_0373 | XALC_0251 | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Probable biotin--[acetyl-coa-carboxylase] ligase protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.494 |