node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IspA | XseB | XALC_2454 | XALC_2453 | Putative geranylgeranyl pyrophosphate synthase protein; Belongs to the FPP/GGPP synthase family. | Putative exonuclease vII small subunit protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.927 |
IspA | folD | XALC_2454 | XALC_1581 | Putative geranylgeranyl pyrophosphate synthase protein; Belongs to the FPP/GGPP synthase family. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.416 |
IspA | mutL | XALC_2454 | XALC_1094 | Putative geranylgeranyl pyrophosphate synthase protein; Belongs to the FPP/GGPP synthase family. | Probable dna mismatch repair protein mutl; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.448 |
IspA | xseA | XALC_2454 | XALC_1090 | Putative geranylgeranyl pyrophosphate synthase protein; Belongs to the FPP/GGPP synthase family. | Probable exodeoxyribonuclease vII large subunit protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.595 |
XALC_1089 | nnrD | XALC_1089 | XALC_1091 | Hypothetical protein. | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.543 |
XALC_1089 | xseA | XALC_1089 | XALC_1090 | Hypothetical protein. | Probable exodeoxyribonuclease vII large subunit protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.773 |
XseB | IspA | XALC_2453 | XALC_2454 | Putative exonuclease vII small subunit protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | Putative geranylgeranyl pyrophosphate synthase protein; Belongs to the FPP/GGPP synthase family. | 0.927 |
XseB | polA | XALC_2453 | XALC_0119 | Putative exonuclease vII small subunit protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | Probable dna polymeraseIprotein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.518 |
XseB | uvrB | XALC_2453 | XALC_1870 | Putative exonuclease vII small subunit protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | Probable excinuclease abc subunit b protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA sub [...] | 0.494 |
XseB | xseA | XALC_2453 | XALC_1090 | Putative exonuclease vII small subunit protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | Probable exodeoxyribonuclease vII large subunit protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.998 |
folD | IspA | XALC_1581 | XALC_2454 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Putative geranylgeranyl pyrophosphate synthase protein; Belongs to the FPP/GGPP synthase family. | 0.416 |
folD | polA | XALC_1581 | XALC_0119 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Probable dna polymeraseIprotein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.514 |
folD | xseA | XALC_1581 | XALC_1090 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Probable exodeoxyribonuclease vII large subunit protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.619 |
mutL | IspA | XALC_1094 | XALC_2454 | Probable dna mismatch repair protein mutl; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Putative geranylgeranyl pyrophosphate synthase protein; Belongs to the FPP/GGPP synthase family. | 0.448 |
mutL | nnrD | XALC_1094 | XALC_1091 | Probable dna mismatch repair protein mutl; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.684 |
mutL | polA | XALC_1094 | XALC_0119 | Probable dna mismatch repair protein mutl; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Probable dna polymeraseIprotein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.950 |
mutL | recN | XALC_1094 | XALC_1680 | Probable dna mismatch repair protein mutl; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Probable dna repair protein recn (recombination protein n); May be involved in recombinational repair of damaged DNA. | 0.497 |
mutL | rnhB | XALC_1094 | XALC_2039 | Probable dna mismatch repair protein mutl; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Probable ribonuclease hII (rnase hII, degrades rna of dna-rna hybrids) protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.428 |
mutL | uvrB | XALC_1094 | XALC_1870 | Probable dna mismatch repair protein mutl; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Probable excinuclease abc subunit b protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA sub [...] | 0.576 |
mutL | xseA | XALC_1094 | XALC_1090 | Probable dna mismatch repair protein mutl; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Probable exodeoxyribonuclease vII large subunit protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.615 |