Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AHA_0804Enterotoxin. (636 aa)    
Predicted Functional Partners:
AHA_0438
Hemolysin; Identified by match to protein family HMM PF01117; match to protein family HMM PF03440.
      
 0.670
AHA_0811
Putative tagatose-6-phosphate ketose/aldose isomerase; Identified by match to protein family HMM PF01380; match to protein family HMM TIGR02815.
 
     0.659
AHA_0104
Extracellular lipase.
     
 0.637
AHA_0028
Ricin-type beta-trefoil lectin domain, putative; Identified by match to protein family HMM PF00652.
     
 0.632
AHA_0809
N-acetylgalactosamine permease IIC component 1; Identified by match to protein family HMM PF03609.
 
     0.625
AHA_0812
D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit; Identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810.
 
     0.617
AHA_0808
N-acetylgalactosamine permease IID component; Identified by match to protein family HMM PF03613.
 
     0.599
AHA_3493
Hemolysin III; Identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065.
      
 0.596
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
      
 0.592
nagA-1
N-acetylglucosamine-6-phosphate deacetylase; Identified by match to protein family HMM PF01979; match to protein family HMM TIGR00221.
 
     0.588
Your Current Organism:
Aeromonas hydrophila
NCBI taxonomy Id: 380703
Other names: A. hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila subsp. hydrophila str. ATCC 7966, Aeromonas hydrophila subsp. hydrophila strain ATCC 7966
Server load: low (12%) [HD]