node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHA_0071 | AHA_2703 | AHA_0071 | AHA_2703 | Conserved hypothetical protein. | Glutamate synthase [NADPH] large chain; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | 0.537 |
AHA_0071 | glnD | AHA_0071 | AHA_1171 | Conserved hypothetical protein. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.543 |
AHA_0071 | glnL | AHA_0071 | AHA_0275 | Conserved hypothetical protein. | Nitrogen regulation protein NR(II); Identified by similarity to SP:P06712; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229. | 0.767 |
AHA_0649 | AHA_2703 | AHA_0649 | AHA_2703 | Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; Belongs to the P(II) protein family. | Glutamate synthase [NADPH] large chain; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | 0.537 |
AHA_0649 | glnD | AHA_0649 | AHA_1171 | Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; Belongs to the P(II) protein family. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.771 |
AHA_0649 | glnE | AHA_0649 | AHA_0771 | Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; Belongs to the P(II) protein family. | Glutamate-ammonia ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.401 |
AHA_0649 | glnL | AHA_0649 | AHA_0275 | Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; Belongs to the P(II) protein family. | Nitrogen regulation protein NR(II); Identified by similarity to SP:P06712; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229. | 0.833 |
AHA_2703 | AHA_0071 | AHA_2703 | AHA_0071 | Glutamate synthase [NADPH] large chain; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Conserved hypothetical protein. | 0.537 |
AHA_2703 | AHA_0649 | AHA_2703 | AHA_0649 | Glutamate synthase [NADPH] large chain; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Nitrogen regulatory protein P-II; Identified by match to protein family HMM PF00543; Belongs to the P(II) protein family. | 0.537 |
AHA_2703 | glnB | AHA_2703 | AHA_0698 | Glutamate synthase [NADPH] large chain; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Nitrogen regulatory protein P-II 1; Identified by similarity to SP:P0A9Z1; match to protein family HMM PF00543; Belongs to the P(II) protein family. | 0.537 |
AHA_2703 | glnD | AHA_2703 | AHA_1171 | Glutamate synthase [NADPH] large chain; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.616 |
AHA_2703 | glnE | AHA_2703 | AHA_0771 | Glutamate synthase [NADPH] large chain; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Glutamate-ammonia ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.530 |
AHA_2703 | glnL | AHA_2703 | AHA_0275 | Glutamate synthase [NADPH] large chain; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | Nitrogen regulation protein NR(II); Identified by similarity to SP:P06712; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229. | 0.530 |
bamA | glnD | AHA_1181 | AHA_1171 | Outer membrane protein, OMP85 family; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.636 |
dapD | glnD | AHA_1170 | AHA_1171 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Identified by match to protein family HMM PF00132; match to protein family HMM TIGR00965; Belongs to the transferase hexapeptide repeat family. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.603 |
dapD | map | AHA_1170 | AHA_1172 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Identified by match to protein family HMM PF00132; match to protein family HMM TIGR00965; Belongs to the transferase hexapeptide repeat family. | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.540 |
glnB | AHA_2703 | AHA_0698 | AHA_2703 | Nitrogen regulatory protein P-II 1; Identified by similarity to SP:P0A9Z1; match to protein family HMM PF00543; Belongs to the P(II) protein family. | Glutamate synthase [NADPH] large chain; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898. | 0.537 |
glnB | glnD | AHA_0698 | AHA_1171 | Nitrogen regulatory protein P-II 1; Identified by similarity to SP:P0A9Z1; match to protein family HMM PF00543; Belongs to the P(II) protein family. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.975 |
glnB | glnE | AHA_0698 | AHA_0771 | Nitrogen regulatory protein P-II 1; Identified by similarity to SP:P0A9Z1; match to protein family HMM PF00543; Belongs to the P(II) protein family. | Glutamate-ammonia ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.405 |
glnB | glnL | AHA_0698 | AHA_0275 | Nitrogen regulatory protein P-II 1; Identified by similarity to SP:P0A9Z1; match to protein family HMM PF00543; Belongs to the P(II) protein family. | Nitrogen regulation protein NR(II); Identified by similarity to SP:P06712; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229. | 0.982 |