node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHA_1046 | nfo | AHA_1046 | AHA_2097 | Helix-turn-helix, AraC type:HhH-GPD:Ada, metal-binding:AlkA, N-terminal; Identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | 0.591 |
AHA_1046 | nth | AHA_1046 | AHA_2640 | Helix-turn-helix, AraC type:HhH-GPD:Ada, metal-binding:AlkA, N-terminal; Identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.518 |
AHA_1046 | polB | AHA_1046 | AHA_2107 | Helix-turn-helix, AraC type:HhH-GPD:Ada, metal-binding:AlkA, N-terminal; Identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029. | DNA polymerase II; Identified by match to protein family HMM PF00136; match to protein family HMM PF03104. | 0.447 |
AHA_1046 | uvrC | AHA_1046 | AHA_2773 | Helix-turn-helix, AraC type:HhH-GPD:Ada, metal-binding:AlkA, N-terminal; Identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.487 |
AHA_1046 | xth | AHA_1046 | AHA_2958 | Helix-turn-helix, AraC type:HhH-GPD:Ada, metal-binding:AlkA, N-terminal; Identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029. | Exodeoxyribonuclease III; Identified by similarity to SP:P09030; match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633. | 0.915 |
AHA_1077 | nfo | AHA_1077 | AHA_2097 | Modification methylase DdeI; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | 0.535 |
AHA_1077 | uvrC | AHA_1077 | AHA_2773 | Modification methylase DdeI; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.510 |
AHA_2098 | nfo | AHA_2098 | AHA_2097 | Oxidoreductase, NAD-binding; Identified by match to protein family HMM PF01408. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | 0.678 |
nfo | AHA_1046 | AHA_2097 | AHA_1046 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | Helix-turn-helix, AraC type:HhH-GPD:Ada, metal-binding:AlkA, N-terminal; Identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029. | 0.591 |
nfo | AHA_1077 | AHA_2097 | AHA_1077 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | Modification methylase DdeI; Identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675. | 0.535 |
nfo | AHA_2098 | AHA_2097 | AHA_2098 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | Oxidoreductase, NAD-binding; Identified by match to protein family HMM PF01408. | 0.678 |
nfo | nth | AHA_2097 | AHA_2640 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.794 |
nfo | polB | AHA_2097 | AHA_2107 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | DNA polymerase II; Identified by match to protein family HMM PF00136; match to protein family HMM PF03104. | 0.539 |
nfo | sapD | AHA_2097 | AHA_1873 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | Peptide ABC transporter, ATP-binding protein SapD; Identified by similarity to SP:P36636; match to protein family HMM PF00005; match to protein family HMM TIGR01727; Belongs to the ABC transporter superfamily. | 0.724 |
nfo | ssb | AHA_2097 | AHA_3957 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.800 |
nfo | ung | AHA_2097 | AHA_3142 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.629 |
nfo | uvrC | AHA_2097 | AHA_2773 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.650 |
nfo | xth | AHA_2097 | AHA_2958 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | Exodeoxyribonuclease III; Identified by similarity to SP:P09030; match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633. | 0.828 |
nth | AHA_1046 | AHA_2640 | AHA_1046 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Helix-turn-helix, AraC type:HhH-GPD:Ada, metal-binding:AlkA, N-terminal; Identified by match to protein family HMM PF00165; match to protein family HMM PF00730; match to protein family HMM PF02805; match to protein family HMM PF06029. | 0.518 |
nth | nfo | AHA_2640 | AHA_2097 | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. | 0.794 |