Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (235 aa)    
Predicted Functional Partners:
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
 
 
 0.934
ftsI
Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
 
 
 0.900
AHA_3259
Identified by match to protein family HMM PF00768; match to protein family HMM PF07943; Belongs to the peptidase S11 family.
  
 
 0.890
dacB
D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Identified by match to protein family HMM PF02113; match to protein family HMM TIGR00666.
     
 0.884
mrcA
Penicillin-binding protein 1A; Identified by similarity to SP:P02918; match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074.
 
 
0.847
mrcB
Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
  
  
0.826
pbpC
Penicillin-binding protein 1C; Identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02073.
  
  
 
0.792
AHA_4113
Cell division protein; Identified by match to protein family HMM PF05036.
   
 
 0.679
AHA_2131
Conserved hypothetical protein; Belongs to the UPF0263 family.
       0.610
AHA_0516
sanA protein; Identified by match to protein family HMM PF02698.
     
 0.548
Your Current Organism:
Aeromonas hydrophila
NCBI taxonomy Id: 380703
Other names: A. hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila subsp. hydrophila ATCC 7966, Aeromonas hydrophila subsp. hydrophila str. ATCC 7966, Aeromonas hydrophila subsp. hydrophila strain ATCC 7966
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