node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHA_2473 | alr-1 | AHA_2473 | AHA_1015 | Dimodular nonribosomal peptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR01733; Belongs to the ATP-dependent AMP-binding enzyme family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Likely plays an important role in supplying D-alanine, which is an indispensable constituent in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the alanine racemase family. | 0.904 |
AHA_2473 | alr-2 | AHA_2473 | AHA_2536 | Dimodular nonribosomal peptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR01733; Belongs to the ATP-dependent AMP-binding enzyme family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.904 |
AHA_2473 | alr-3 | AHA_2473 | AHA_2607 | Dimodular nonribosomal peptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR01733; Belongs to the ATP-dependent AMP-binding enzyme family. | Alanine racemase; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes ten of the 19 natural chiral amino acids known, including both non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Cys, Gln and Asn) and positively charged amino acids (His, Lys and Arg). Is not active on negatively charged (Glu and Asp) or aromatic (Tyr, Trp and Phe) amino acids and displays minimal activity towards beta-branched aliphatic (Ile, Val and Thr) substrates. Enables bacteria to produce and release extracellular non-canonical D-amino acids (NCDAAs) that regulate [...] | 0.904 |
AHA_2473 | ddl | AHA_2473 | AHA_2404 | Dimodular nonribosomal peptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR01733; Belongs to the ATP-dependent AMP-binding enzyme family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.911 |
alr-1 | AHA_2473 | AHA_1015 | AHA_2473 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Likely plays an important role in supplying D-alanine, which is an indispensable constituent in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the alanine racemase family. | Dimodular nonribosomal peptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR01733; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.904 |
alr-1 | alr-2 | AHA_1015 | AHA_2536 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Likely plays an important role in supplying D-alanine, which is an indispensable constituent in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the alanine racemase family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.902 |
alr-1 | alr-3 | AHA_1015 | AHA_2607 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Likely plays an important role in supplying D-alanine, which is an indispensable constituent in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the alanine racemase family. | Alanine racemase; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes ten of the 19 natural chiral amino acids known, including both non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Cys, Gln and Asn) and positively charged amino acids (His, Lys and Arg). Is not active on negatively charged (Glu and Asp) or aromatic (Tyr, Trp and Phe) amino acids and displays minimal activity towards beta-branched aliphatic (Ile, Val and Thr) substrates. Enables bacteria to produce and release extracellular non-canonical D-amino acids (NCDAAs) that regulate [...] | 0.926 |
alr-1 | ddl | AHA_1015 | AHA_2404 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Likely plays an important role in supplying D-alanine, which is an indispensable constituent in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the alanine racemase family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.941 |
alr-1 | murC | AHA_1015 | AHA_3883 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Likely plays an important role in supplying D-alanine, which is an indispensable constituent in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the alanine racemase family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.507 |
alr-1 | murD | AHA_1015 | AHA_3886 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Likely plays an important role in supplying D-alanine, which is an indispensable constituent in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the alanine racemase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.597 |
alr-1 | murF | AHA_1015 | AHA_3888 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Likely plays an important role in supplying D-alanine, which is an indispensable constituent in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the alanine racemase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.951 |
alr-2 | AHA_2473 | AHA_2536 | AHA_2473 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Dimodular nonribosomal peptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR01733; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.904 |
alr-2 | alr-1 | AHA_2536 | AHA_1015 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Likely plays an important role in supplying D-alanine, which is an indispensable constituent in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the alanine racemase family. | 0.902 |
alr-2 | alr-3 | AHA_2536 | AHA_2607 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Alanine racemase; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes ten of the 19 natural chiral amino acids known, including both non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Cys, Gln and Asn) and positively charged amino acids (His, Lys and Arg). Is not active on negatively charged (Glu and Asp) or aromatic (Tyr, Trp and Phe) amino acids and displays minimal activity towards beta-branched aliphatic (Ile, Val and Thr) substrates. Enables bacteria to produce and release extracellular non-canonical D-amino acids (NCDAAs) that regulate [...] | 0.940 |
alr-2 | ddl | AHA_2536 | AHA_2404 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.941 |
alr-2 | murC | AHA_2536 | AHA_3883 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.523 |
alr-2 | murD | AHA_2536 | AHA_3886 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.626 |
alr-2 | murF | AHA_2536 | AHA_3888 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.951 |
alr-3 | AHA_2473 | AHA_2607 | AHA_2473 | Alanine racemase; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes ten of the 19 natural chiral amino acids known, including both non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Cys, Gln and Asn) and positively charged amino acids (His, Lys and Arg). Is not active on negatively charged (Glu and Asp) or aromatic (Tyr, Trp and Phe) amino acids and displays minimal activity towards beta-branched aliphatic (Ile, Val and Thr) substrates. Enables bacteria to produce and release extracellular non-canonical D-amino acids (NCDAAs) that regulate [...] | Dimodular nonribosomal peptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR01733; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.904 |
alr-3 | alr-1 | AHA_2607 | AHA_1015 | Alanine racemase; Amino-acid racemase able to utilize a broad range of substrates. Reversibly racemizes ten of the 19 natural chiral amino acids known, including both non-beta-branched aliphatic amino acids (Ala, Leu, Met, Ser, Cys, Gln and Asn) and positively charged amino acids (His, Lys and Arg). Is not active on negatively charged (Glu and Asp) or aromatic (Tyr, Trp and Phe) amino acids and displays minimal activity towards beta-branched aliphatic (Ile, Val and Thr) substrates. Enables bacteria to produce and release extracellular non-canonical D-amino acids (NCDAAs) that regulate [...] | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Likely plays an important role in supplying D-alanine, which is an indispensable constituent in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the alanine racemase family. | 0.926 |