STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3XNA0_ASPNARNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (478 aa)    
Predicted Functional Partners:
G3XLK7_ASPNA
TFIIH basal transcription factor complex, subunit SSL2/RAD25.
   
 0.998
G3XLV9_ASPNA
General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.
   
 0.998
G3XMB0_ASPNA
Uncharacterized protein.
    
 0.998
G3YDV8_ASPNA
Uncharacterized protein.
   
 0.998
G3YEQ3_ASPNA
DNA repair helicase, subunit of TFIIH.
  
 
 0.997
G3Y917_ASPNA
Uncharacterized protein.
    
 0.994
G3XVB1_ASPNA
Transcription initiation factor TFIIE, alpha subunit.
   
 0.993
G3YFL9_ASPNA
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
    
 0.989
G3Y4C9_ASPNA
CYCLIN domain-containing protein; Belongs to the cyclin family.
    
 0.988
G3XTE7_ASPNA
Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.
    
 0.987
Your Current Organism:
Aspergillus niger
NCBI taxonomy Id: 380704
Other names: A. niger ATCC 1015, Aspergillus niger ATCC 1015
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.