STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GET3ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (326 aa)    
Predicted Functional Partners:
GET1
Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
    
 0.990
G3XXD4_ASPNA
Uncharacterized protein.
    
 0.986
G3Y4P5_ASPNA
Uncharacterized protein.
   
 0.960
G3Y9Y3_ASPNA
Uncharacterized protein.
    
 0.947
G3YFZ3_ASPNA
STI1 domain-containing protein.
   
 0.901
G3XRV1_ASPNA
Uncharacterized protein.
    
 0.846
G3XQ97_ASPNA
Uncharacterized protein.
    
 0.838
G3Y3X6_ASPNA
Zn(2)-C6 fungal-type domain-containing protein.
    
 0.838
G3Y8D1_ASPNA
Uncharacterized protein.
    
 0.838
G3Y9D9_ASPNA
Uncharacterized protein.
    
 0.838
Your Current Organism:
Aspergillus niger
NCBI taxonomy Id: 380704
Other names: A. niger ATCC 1015, Aspergillus niger ATCC 1015
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