STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACG57334.1TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; KEGG: mma:MM_0209 hypothetical protein. (146 aa)    
Predicted Functional Partners:
ACG57774.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.998
ACG58125.1
PFAM: PHP domain protein; SMART: DNA polymerase X; phosphoesterase PHP domain protein; KEGG: aae:aq_1422 hypothetical DNA polymerase / putative histidinol phosphatase.
  
 0.993
ACG57826.1
KEGG: dps:DP0107 similar to signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein.
    
 0.949
ACG56728.1
PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein class 2; KEGG: aae:aq_1628 DNA polymerase I 3'-5' exo domain.
  
 0.948
ACG58110.1
PFAM: SNF2-related protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicases; KEGG: sul:SYO3AOP1_0490 helicase domain protein.
   
 
 0.870
ACG57459.1
PFAM: SMC domain protein; KEGG: aae:aq_1006 exonuclease SbcC.
   
 0.846
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
 0.835
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
    0.820
pdxJ
Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
       0.773
ACG57153.1
SMART: helicase c2; DEAD-like helicases; KEGG: aae:aq_358 ATP-dependent helicase (DinG family).
   
 
 0.769
Your Current Organism:
Hydrogenobaculum sp. Y04AAS1
NCBI taxonomy Id: 380749
Other names: H. sp. Y04AAS1
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