STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OBQ61262.1Isocitrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (403 aa)    
Predicted Functional Partners:
OBQ63418.1
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.991
OBQ63442.1
2-oxoglutarate dehydrogenase E1 component; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.987
OBQ62426.1
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.981
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.933
gcvP
Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
  
 0.916
OBQ75515.1
Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.907
OBQ59387.1
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.903
fhs
Formate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family.
 
 
  
 0.887
OBQ68063.1
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.840
OBQ73723.1
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.840
Your Current Organism:
Mesorhizobium loti
NCBI taxonomy Id: 381
Other names: ATCC 700743, CCUG 27878, DSM 2626, IFO 14779, JCM 21464, LMG 6125, LMG:6125, M. loti, Mesorhizobium sp. LMG 6125, NBRC 14779, NZP 2213, Rhizobium loti
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