STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OBQ59279.16-O-methylguanine DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)    
Predicted Functional Partners:
OBQ71052.1
6-O-methylguanine DNA methyltransferase; Regulates genes involved in the repair of alkylated DNA; repairs DNA containing 6-O-methylguanine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
0.623
polA
Hypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.591
OBQ59280.1
Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.542
OBQ57999.1
DNA-3-methyladenine glycosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.496
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.468
OBQ69681.1
RNA polymerase factor sigma-32; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family.
  
 
 0.462
OBQ66448.1
RNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
 
 0.462
OBQ59278.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.434
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
     
 0.427
OBQ67531.1
Hybrid-cluster NAD(P)-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.421
Your Current Organism:
Mesorhizobium loti
NCBI taxonomy Id: 381
Other names: ATCC 700743, CCUG 27878, DSM 2626, IFO 14779, JCM 21464, LMG 6125, LMG:6125, M. loti, Mesorhizobium sp. LMG 6125, NBRC 14779, NZP 2213, Rhizobium loti
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.