STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OCA5Oxidant-induced cell-cycle arrest protein 5. (566 aa)    
Predicted Functional Partners:
C5E3E0_LACTC
Citrate synthase; Belongs to the citrate synthase family.
  
 0.743
C5DC41_LACTC
KLTH0A07612p.
    
 
 0.705
C5DLP8_LACTC
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.663
C5DBE6_LACTC
KLTH0A01958p.
  
 
 0.653
C5E1Z5_LACTC
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.646
C5DMK1_LACTC
KLTH0G09592p.
    
 
 0.634
C5DER4_LACTC
KLTH0C11462p.
  
 0.628
C5DG09_LACTC
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.613
C5DMM6_LACTC
KLTH0G10142p.
  
 0.613
C5DB75_LACTC
KLTH0A00110p.
  
 
 0.585
Your Current Organism:
Lachancea thermotolerans
NCBI taxonomy Id: 559295
Other names: Kluyveromyces thermotolerans CBS 6340, L. thermotolerans CBS 6340, Lachancea thermotolerans CBS 6340
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.