SDZ07819.1 protein (Herbiconiux ginsengi) - STRING interaction network

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second shell of interactors

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filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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Score

SDZ07819.1

NlpC/P60 family protein. (425 aa)

Predicted Functional Partners:

SDZ07804.1

0.645

SDZ08800.1

0.595

ftsE

0.476

SDZ07751.1

0.458

SDZ14767.1

0.432

SDZ07837.1

0.423

SDZ29278.1

0.423

SDZ07782.1

0.402

SDZ07590.1

0.400

Your Current Organism:

Herbiconiux ginsengi

NCBI taxonomy Id: 381665
Other names: CGMCC 4.3491, DSM 19088, H. ginsengi, Herbiconiux ginsengi (Qiu et al. 2007) Behrendt et al. 2011, JCM 13908, Leifsonia ginsengi, Leifsonia ginsengi Qiu et al. 2007, Leifsonia sp. wged11, NBRC 104580, strain wged11

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDZ07590.1	SDZ07751.1	SAMN05216554_2268	SAMN05216554_2279	Hypothetical protein.	Protein of unknown function.	0.767
SDZ07590.1	SDZ07819.1	SAMN05216554_2268	SAMN05216554_2284	Hypothetical protein.	NlpC/P60 family protein.	0.400
SDZ07751.1	SDZ07590.1	SAMN05216554_2279	SAMN05216554_2268	Protein of unknown function.	Hypothetical protein.	0.767
SDZ07751.1	SDZ07782.1	SAMN05216554_2279	SAMN05216554_2281	Protein of unknown function.	Transglutaminase-like enzyme, putative cysteine protease.	0.495
SDZ07751.1	SDZ07819.1	SAMN05216554_2279	SAMN05216554_2284	Protein of unknown function.	NlpC/P60 family protein.	0.458
SDZ07751.1	SDZ29278.1	SAMN05216554_2279	SAMN05216554_3087	Protein of unknown function.	D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6).	0.630
SDZ07782.1	SDZ07751.1	SAMN05216554_2281	SAMN05216554_2279	Transglutaminase-like enzyme, putative cysteine protease.	Protein of unknown function.	0.495
SDZ07782.1	SDZ07804.1	SAMN05216554_2281	SAMN05216554_2283	Transglutaminase-like enzyme, putative cysteine protease.	Hypothetical protein.	0.453
SDZ07782.1	SDZ07819.1	SAMN05216554_2281	SAMN05216554_2284	Transglutaminase-like enzyme, putative cysteine protease.	NlpC/P60 family protein.	0.402
SDZ07804.1	SDZ07782.1	SAMN05216554_2283	SAMN05216554_2281	Hypothetical protein.	Transglutaminase-like enzyme, putative cysteine protease.	0.453
SDZ07804.1	SDZ07819.1	SAMN05216554_2283	SAMN05216554_2284	Hypothetical protein.	NlpC/P60 family protein.	0.645
SDZ07819.1	SDZ07590.1	SAMN05216554_2284	SAMN05216554_2268	NlpC/P60 family protein.	Hypothetical protein.	0.400
SDZ07819.1	SDZ07751.1	SAMN05216554_2284	SAMN05216554_2279	NlpC/P60 family protein.	Protein of unknown function.	0.458
SDZ07819.1	SDZ07782.1	SAMN05216554_2284	SAMN05216554_2281	NlpC/P60 family protein.	Transglutaminase-like enzyme, putative cysteine protease.	0.402
SDZ07819.1	SDZ07804.1	SAMN05216554_2284	SAMN05216554_2283	NlpC/P60 family protein.	Hypothetical protein.	0.645
SDZ07819.1	SDZ07837.1	SAMN05216554_2284	SAMN05216554_2285	NlpC/P60 family protein.	Putative glutamine amidotransferase.	0.423
SDZ07819.1	SDZ08800.1	SAMN05216554_2284	SAMN05216554_2332	NlpC/P60 family protein.	Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.	0.595
SDZ07819.1	SDZ14767.1	SAMN05216554_2284	SAMN05216554_2634	NlpC/P60 family protein.	Protein of unknown function.	0.432
SDZ07819.1	SDZ29278.1	SAMN05216554_2284	SAMN05216554_3087	NlpC/P60 family protein.	D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6).	0.423
SDZ07819.1	ftsE	SAMN05216554_2284	SAMN05216554_2333	NlpC/P60 family protein.	Cell division transport system ATP-binding protein; Part of the ABC transporter FtsEX involved in cellular division.	0.476

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Network Stats

number of nodes:

4

number of edges:

5

average node degree:

2.5

avg. local clustering coefficient:

0.833

expected number of edges:

3

PPI enrichment p-value:

0.157

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0034614

Cellular response to reactive oxygen species

3 of 47

1.93

1.13

0.0062

GO:0007623

Circadian rhythm

3 of 73

1.74

1.04

0.0081

GO:0048511

Rhythmic process

4 of 147

1.56

1.03

0.0062

GO:0043923

Positive regulation by host of viral transcription

2 of 11

2.38

1.0

0.0143

GO:0070848

Response to growth factor

5 of 252

1.42

0.97

0.0062

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0001221

Transcription coregulator binding

3 of 52

1.88

1.01

0.0107

GO:0061629

RNA polymerase II-specific DNA-binding transcription factor binding

4 of 192

1.44

0.89

0.0107

GO:0004707

MAP kinase activity

2 of 15

2.25

0.86

0.0261

GO:0004402

Histone acetyltransferase activity

2 of 18

2.17

0.83

0.0284

GO:0001223

Transcription coactivator binding

2 of 19

2.14

0.83

0.0284

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005667

Transcription regulator complex

5 of 292

1.36

1.1

0.0018

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7591

Basic region leucin zipper, and CREB phosphorylation

4 of 17

2.49

2.9

3.23e-06

CL:7383

Mixed, incl. Nuclear Receptor transcription pathway, and Basic region leucin zipper

5 of 134

1.69

1.93

3.33e-05

CL:7595

ATF4-CREB1 transcription factor complex, and CREB3 factors activate genes

2 of 5

2.72

1.24

0.0056

CL:7613

PERK regulates gene expression, and Transcription factor AP-1 complex

2 of 6

2.64

1.2

0.0064

CL:6497

Mixed, incl. NGF-stimulated transcription, and Regulation of DNA-templated DNA replication initiation

2 of 6

2.64

1.2

0.0064

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04912

GnRH signaling pathway

3 of 90

1.64

1.02

0.0078

map04916

Melanogenesis

3 of 93

1.63

1.01

0.0078

map04010

MAPK signaling pathway

4 of 307

1.24

0.84

0.0078

map04310

Wnt signaling pathway

3 of 173

1.36

0.83

0.0130

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-198725

Nuclear Events (kinase and transcription factor activation)

5 of 35

2.28

3.5

9.07e-08

MAP-450282

MAPK targets/ Nuclear events mediated by MAP kinases

4 of 28

2.28

2.84

2.58e-06

MAP-187037

Signaling by NTRK1 (TRKA)

5 of 72

1.96

2.71

1.35e-06

MAP-166520

Signaling by NTRKs

5 of 87

1.88

2.54

2.22e-06

MAP-450294

MAP kinase activation

4 of 49

2.03

2.33

1.67e-05

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF09030

Creb binding

2 of 2

3.12

1.25

0.0056

PF02172

KIX domain

2 of 2

3.12

1.25

0.0056

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01250

Histone acetylation protein

2 of 2

3.12

1.54

0.0017

SM00551

TAZ zinc finger, present in p300 and CBP

2 of 2

3.12

1.54

0.0017

SM00338

Basic region leucin zipper

3 of 34

2.07

1.43

0.0017

SM00291

Zinc-binding domain, present in Dystrophin, CREB-binding protein.

2 of 16

2.22

1.0

0.0138

SM00297

Bromo domain

2 of 33

1.9

0.72

0.0428

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