STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDZ43090.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (530 aa)    
Predicted Functional Partners:
SDY40023.1
Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
 
 0.983
SDZ50766.1
Lactate dehydrogenase.
 
  
 
0.834
gpmA
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
  0.819
SDZ05645.1
Probable phosphoglycerate mutase.
    
  0.812
SDZ27034.1
Malate synthase; Belongs to the malate synthase family.
     
 0.779
SDY71181.1
Phosphoglycolate phosphatase.
    
 0.768
SDZ27018.1
Isocitrate lyase.
   
 
  0.767
rplF
Large subunit ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
   0.755
rplB
LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
    
   0.752
rplQ
LSU ribosomal protein L17P.
   
   0.751
Your Current Organism:
Herbiconiux ginsengi
NCBI taxonomy Id: 381665
Other names: CGMCC 4.3491, DSM 19088, H. ginsengi, Herbiconiux ginsengi (Qiu et al. 2007) Behrendt et al. 2011, JCM 13908, Leifsonia ginsengi, Leifsonia ginsengi Qiu et al. 2007, Leifsonia sp. wged11, NBRC 104580, strain wged11
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.