STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sbm1Methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1096 aa)    
Predicted Functional Partners:
sbm2
Methylmalonyl-CoA mutase.
 
 
0.995
h16_B1841
Methylmalonyl-CoA mutase c-terminal domain/subunit (cobalamin-binding).
 
0.963
h16_B1842
Methylmalonyl-CoA mutase alpha subunit.
 
 
0.939
h16_B1839
Transport system kinase.
 
  
0.893
h16_A0163
Putative periplasmic metal ion binding protein.
 
  
 0.855
h16_A1358
Acetyl-CoA hydrolase.
  
  
 0.788
h16_B1368
Acetyl-CoA hydrolase/transferase.
  
  
 0.788
h16_A0461
Two domain protein: 3-hydroxyacyl-CoA dehydrogenase.
 
  
 0.680
btuF
Cobalamin-binding protein (BtuF).
 
  
 0.646
paaH1
3-Hydroxyacyl-CoA dehydrogenase.
 
   
 0.632
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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