STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
parA2ATPase involved in chromosome partitioning. (257 aa)    
Predicted Functional Partners:
parB4
Chromosome partitioning protein ParB; Belongs to the ParB family.
 
 0.998
gidB
S-Adenosylmethionine-dependent methyltransferase involved in bacterial cell division; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
 
  
 0.891
parB3
Chromosome partitioning protein ParB; Belongs to the ParB family.
 
 
 0.866
h16_A1582
DNA segregation ATPase FtsK/SpoIIIE related protein.
 
  
 0.776
ftsK
DNA segregation ATPase ftsk/spoIIIE proteins; 5 TMHs.
 
  
 0.764
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
 
 
 0.740
nadB
L-Aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
  
 0.707
h16_A0512
Peptidyl-prolyl cis-trans isomerase (rotamase c)protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
     
 0.655
h16_A0119
Site-specific recombinase XerC/Integrase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
  
   
 0.644
pcaQ
Transcriptional regulator, LysR-family; Belongs to the LysR transcriptional regulatory family.
   
  
 0.621
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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