STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prpD22-Methylcitrate dehydratase. (460 aa)    
Predicted Functional Partners:
citE3
Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.
  
 0.934
h16_B0679
Conserved hypothetical protein; Function unknown.
 
  
 0.906
h16_B0683
Acyl-CoA dehydrogenase.
 
  
 0.759
prpC1
2-Methylcitrate synthase 1; Belongs to the citrate synthase family.
  
 
 0.749
prpC2
2-Methylcitrate synthase 2; Belongs to the citrate synthase family.
  
 
 0.749
citE4
Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.
  
 0.747
h16_B0682
Predicted acyl-CoA transferase/carnitine dehydratase; Belongs to the CoA-transferase III family.
 
    0.712
h16_B0614
Lactoylglutathione lyase or related lyase.
 
    0.703
prpB
Methylisocitric acid lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
  
  
 0.699
h16_B2211
Citrate synthase.
 
  
 0.607
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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