STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbbBFormate dehydrogenase, alpha chain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (757 aa)    
Predicted Functional Partners:
fdhD2
Protein required for formate dehydrogenase activity; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
  
 0.852
fdsC
Uncharacterized protein required for formate dehydrogenase activity; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
  
 0.842
fdhB1
Formate dehydrogenase iron-sulfur subunit; HybA.
  
 
 0.830
fdoH
Formate dehydrogenase beta subunit.
  
 
 0.830
h16_B2320
Cytochrome c2 precursor.
  
 
 0.735
gltB1
Glutamate synthase [NADPH], Glutamate synthase amidotransferase domain.
  
 
 0.672
qcrA
Ubiquinol-cytochrome c reductase, iron-sulfur subunit (Rieske Fe-S protein); Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
 
 0.659
ccoO
Cbb3-type cytochrome oxidase, monoheme subunit II; 1 TMHs.
  
  
 0.649
fdhC
Cytochrome b subunit of formate dehydrogenase; 5 TMHs.
  
 
 0.604
fdoI
Formate dehydrogenase gamma subunit; 4 TMHs.
  
 
 0.604
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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