STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
h16_B2254MFS transporter, AzgA family; 12 TMHs. (464 aa)    
Predicted Functional Partners:
purL
Phosphoribosyl-formylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.886
apt
Adenine/guanine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
  
 0.584
purE
Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
  
 0.550
purD
Phosphoribosylamine-glycine ligase; Belongs to the GARS family.
  
  
 0.550
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase).
  
  
 0.543
h16_A0806
Nucleobase:cation symporter 2 (NCS2) family transporter; 11 TMHs.
 
  
 0.543
purK
Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
  
  
 0.540
h16_B1490
Nucleobase:cation symporter 2 (NCS2) family transporter; 12 TMHs.
 
  
 0.536
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
  
  
 0.527
h16_B0861
Nucleobase:cation symporter 2 (NCS2) family transporter; 12 TMHs.
 
  
 0.514
Your Current Organism:
Cupriavidus necator
NCBI taxonomy Id: 381666
Other names: Alcaligenes eutropha H16, C. necator H16, Cupriavidus necator ATCC 17699, Cupriavidus necator H16, Ralstonia eutropha ATCC 17699, Ralstonia eutropha H16, Ralstonia eutropha str. H16, Ralstonia eutropha strain H16, Wautersia eutropha H16
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