STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
SHK17757.1acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (628 aa)    
Predicted Functional Partners:
SHK18852.1
citryl-CoA lyase.
  
 0.995
SHK14639.1
Pyruvate carboxylase subunit B.
    
 0.971
accD
acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
    
 0.964
SHK51347.1
(R)-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.963
SHK38439.1
Pyruvate ferredoxin oxidoreductase gamma subunit.
  
 
 0.958
SHK38517.1
Pyruvate ferredoxin oxidoreductase alpha subunit.
  
 
 0.958
SHK41856.1
Pyruvate ferredoxin oxidoreductase alpha subunit.
  
 
 0.958
SHK41914.1
Pyruvate ferredoxin oxidoreductase gamma subunit.
  
 
 0.958
SHK46389.1
acetyl-CoA carboxylase, biotin carboxylase subunit.
  
 0.958
accA
acetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
    
 0.957
Your Current Organism:
Thermocrinis minervae
NCBI taxonomy Id: 381751
Other names: Aquificaceae bacterium CR11, Aquificaceae sp. CR11, DSM 19557, T. minervae, Thermocrinis minervae Caldwell et al. 2010, strain CR11
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