STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmHProtein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (153 aa)    
Predicted Functional Partners:
Fnod_1657
Ribosomal L11 methyltransferase; PFAM: protein of unknown function Met10; methyltransferase small; ribosomal L11 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: tma:TM1079 ribosomal protein L11 methyltransferase, putative.
 
   
 0.795
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
  
 0.774
Fnod_1655
PFAM: protein of unknown function DUF88; KEGG: bam:Bamb_1072 protein of unknown function DUF88.
       0.702
Fnod_1656
PFAM: protein of unknown function DUF501; KEGG: tpt:Tpet_1666 protein of unknown function DUF501.
       0.702
Fnod_1658
Peptidase M23B; PFAM: Peptidoglycan-binding LysM; peptidase M23B; KEGG: tpt:Tpet_0511 peptidase M23B.
  
    0.596
Fnod_1653
Putative anti-sigma-28 factor, FlgM; KEGG: tma:TM0085 negative regulator of flagellin synthesis FlgM.
     
 0.574
Fnod_1415
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.570
Fnod_1652
Hypothetical protein.
       0.566
Fnod_1649
PFAM: methyltransferase small; Methyltransferase type 11; KEGG: tpt:Tpet_0239 methyltransferase type 11.
 
    0.535
mnmG
Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
  
  
 0.524
Your Current Organism:
Fervidobacterium nodosum
NCBI taxonomy Id: 381764
Other names: F. nodosum Rt17-B1, Fervidobacterium nodosum Rt17-B1, Fervidobacterium nodosum str. Rt17-B1, Fervidobacterium nodosum strain Rt17-B1
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