Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
betACholine dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. (549 aa)    
Predicted Functional Partners:
betB
Betaine-aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.
 
 0.989
betC
Choline-sulfatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.942
betI
Transcriptional regulator; Repressor involved in choline regulation of the bet genes.
 
  
 0.910
AIL99578.1
Choline transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.807
AIL98187.1
SAM-dependent methlyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.800
psd
Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
     
  0.800
choW
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.739
glcE
2-hydroxy-acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.733
proV
Hemolysin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.625
AIL98215.1
Ankyrin; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.514
Your Current Organism:
Sinorhizobium meliloti
NCBI taxonomy Id: 382
Other names: ATCC 9930, CCUG 27879, CFBP 5561, DSM 30135, Ensifer meliloti, Ensifer sp. AC50a, Ensifer sp. AC50e, HAMBI 2148, IAM 12611, ICMP 12623, IFO 14782, JCM 20682, LMG 6133, LMG:6133, NBRC 14782, NCAIM B.01520, NRRL L-45, NZP 4027, Rhizobium meliloti, Rhizobium meliloti (megaplasmid pRME41B SYM), Rhizobium meliloti (plasmid pRmeGR4b), Rhizobium meliloti plasmid pRmeGR4b, Rhizobium sp. AC50e, S. meliloti
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