Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AIL99674.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)    
Predicted Functional Partners:
AIL98834.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.680
AIL99251.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.678
rdgB
Purine NTP phosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
   
   0.661
AIM00675.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.637
AIL99673.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.631
AIM00665.1
Flagellar export protein FliJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.627
AIL99319.1
ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.614
AIM00368.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.604
AIL99306.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.593
AIL99710.1
Signal peptide protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.590
Your Current Organism:
Sinorhizobium meliloti
NCBI taxonomy Id: 382
Other names: ATCC 9930, CCUG 27879, CFBP 5561, DSM 30135, Ensifer meliloti, Ensifer sp. AC50a, Ensifer sp. AC50e, HAMBI 2148, IAM 12611, ICMP 12623, IFO 14782, JCM 20682, LMG 6133, LMG:6133, NBRC 14782, NCAIM B.01520, NRRL L-45, NZP 4027, Rhizobium meliloti, Rhizobium meliloti (megaplasmid pRME41B SYM), Rhizobium meliloti (plasmid pRmeGR4b), Rhizobium meliloti plasmid pRmeGR4b, Rhizobium sp. AC50e, S. meliloti
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