Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AIM00395.1Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)    
Predicted Functional Partners:
AIM00396.1
Dihydropyrimidine dehydrogenase; NADH-dependent; catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
AIM00757.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
dhp
Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.975
nuoF
NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
 
 
 0.967
AIM00948.1
Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.967
AIL97936.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family.
 
 
 0.922
AIM00946.1
Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.914
hyuC
Allantoate amidohydrolase; May be involved in the asymmetric conversion of racemic 5- substituted hydantoins to the corresponding L-amino acids. Catalyzes specifically the conversion of N-carbamoyl-L-amino acids to free L- amino acids in an irreversible reaction. N-carbamoyl-L-methionine is the best substrate. HyuC of R.meliloti is the first L-N-carbamoylase that hydrolyzes N-carbamoyl-L-tryptophan as well as N-carbamoyl-L-amino acids with aliphatic substituents; Belongs to the peptidase M20 family.
 
 
 0.913
deoA
Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
     
  0.900
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
     
  0.900
Your Current Organism:
Sinorhizobium meliloti
NCBI taxonomy Id: 382
Other names: ATCC 9930, CCUG 27879, CFBP 5561, DSM 30135, Ensifer meliloti, Ensifer sp. AC50a, Ensifer sp. AC50e, HAMBI 2148, IAM 12611, ICMP 12623, IFO 14782, JCM 20682, LMG 6133, LMG:6133, NBRC 14782, NCAIM B.01520, NRRL L-45, NZP 4027, Rhizobium meliloti, Rhizobium meliloti (megaplasmid pRME41B SYM), Rhizobium meliloti (plasmid pRmeGR4b), Rhizobium meliloti plasmid pRmeGR4b, Rhizobium sp. AC50e, S. meliloti
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