STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hyuCAllantoate amidohydrolase; May be involved in the asymmetric conversion of racemic 5- substituted hydantoins to the corresponding L-amino acids. Catalyzes specifically the conversion of N-carbamoyl-L-amino acids to free L- amino acids in an irreversible reaction. N-carbamoyl-L-methionine is the best substrate. HyuC of R.meliloti is the first L-N-carbamoylase that hydrolyzes N-carbamoyl-L-tryptophan as well as N-carbamoyl-L-amino acids with aliphatic substituents; Belongs to the peptidase M20 family. (416 aa)    
Predicted Functional Partners:
dhp
Dihydropyrimidinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.993
AIM00396.1
Dihydropyrimidine dehydrogenase; NADH-dependent; catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.955
AIM00395.1
Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.909
AIM00453.1
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
   
 0.806
AIM01165.1
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
   
 0.806
AIL97906.1
Hydantoinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.654
rutR
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.624
AIM00408.1
Nitrate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.522
AIL98874.1
Histidinol-phosphate aminotransferase; Catalyzes the formation of histidinol phosphate and 2-oxoglutarate from glutamate and imidazole acetol-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.510
AIM00406.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.496
Your Current Organism:
Sinorhizobium meliloti
NCBI taxonomy Id: 382
Other names: ATCC 9930, CCUG 27879, CFBP 5561, DSM 30135, Ensifer meliloti, Ensifer sp. AC50a, Ensifer sp. AC50e, HAMBI 2148, IAM 12611, ICMP 12623, IFO 14782, JCM 20682, LMG 6133, LMG:6133, NBRC 14782, NCAIM B.01520, NRRL L-45, NZP 4027, Rhizobium meliloti, Rhizobium meliloti (megaplasmid pRME41B SYM), Rhizobium meliloti (plasmid pRmeGR4b), Rhizobium meliloti plasmid pRmeGR4b, Rhizobium sp. AC50e, S. meliloti
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.