Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AIM01192.1Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (227 aa)    
Predicted Functional Partners:
AIL99668.1
SulP family sulfate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.939
AIL99779.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.843
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
   
    0.619
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.619
pdxY
Pyridoxamine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyridoxine kinase family.
       0.600
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.597
AIM00757.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.427
Your Current Organism:
Sinorhizobium meliloti
NCBI taxonomy Id: 382
Other names: ATCC 9930, CCUG 27879, CFBP 5561, DSM 30135, Ensifer meliloti, Ensifer sp. AC50a, Ensifer sp. AC50e, HAMBI 2148, IAM 12611, ICMP 12623, IFO 14782, JCM 20682, LMG 6133, LMG:6133, NBRC 14782, NCAIM B.01520, NRRL L-45, NZP 4027, Rhizobium meliloti, Rhizobium meliloti (megaplasmid pRME41B SYM), Rhizobium meliloti (plasmid pRmeGR4b), Rhizobium meliloti plasmid pRmeGR4b, Rhizobium sp. AC50e, S. meliloti
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.