STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDY81962.1C-5 cytosine-specific DNA methylase superfamily; [L] COG0270 Site-specific DNA methylase. (349 aa)    
Predicted Functional Partners:
EDY82235.1
DNA mismatch endonuclease Vsr family; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.
 
   
 0.789
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.633
EDY80943.1
[L] COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family.
 
  
 0.618
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.577
EDY82532.1
Hypothetical protein.
  
    0.529
EDY84778.1
Phosphorylase family; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
  0.441
EDY80528.1
RmlD substrate binding domain superfamily; [R] COG1073 Hydrolases of the alpha/beta superfamily.
  
  
  0.431
EDY83404.1
[R] COG1988 Predicted membrane-bound metal-dependent hydrolases.
   
    0.429
Your Current Organism:
Verrucomicrobiae bacterium DG1235
NCBI taxonomy Id: 382464
Other names: V. bacterium DG1235, Verrucomicrobiae bacterium str. DG1235, Verrucomicrobiae bacterium strain DG1235, Verrucomicrobiales bacterium DG1235
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.