STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (312 aa)    
Predicted Functional Partners:
cobQ
CobB/CobQ-like glutamine amidotransferase domain protein; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
 0.967
EDY83294.1
Adenosylcobinamide amidohydrolase domain protein; [S] COG1865 Uncharacterized conserved protein.
 
  
 0.812
EDY83004.1
uroporphyrin-III C-methyltransferase domain protein; [H] COG0007 Uroporphyrinogen-III methylase.
 
   
 0.801
EDY82858.1
ATP:cob(I)alamin adenosyltransferase; [S] COG2096 Uncharacterized conserved protein; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.798
EDY83079.1
ABC transporter, ATP-binding protein; [PH] COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.
 
  
 0.721
EDY84553.1
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
   
 0.650
EDY82493.1
[H] COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
   
 0.620
EDY80989.1
[I] COG1267 Phosphatidylglycerophosphatase A and related proteins.
    
  0.512
EDY84051.1
Hypothetical protein.
       0.511
EDY80990.1
ABC transporter, FeCT family, permease protein; [P] COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
   
 0.510
Your Current Organism:
Verrucomicrobiae bacterium DG1235
NCBI taxonomy Id: 382464
Other names: V. bacterium DG1235, Verrucomicrobiae bacterium str. DG1235, Verrucomicrobiae bacterium strain DG1235, Verrucomicrobiales bacterium DG1235
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.