STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDY83048.1Kinase, pfkB family; [G] COG0524 Sugar kinases, ribokinase family; Belongs to the carbohydrate kinase PfkB family. (327 aa)    
Predicted Functional Partners:
guaA
GMP synthase, C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.787
carB
Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family.
  
 0.757
nagB
Glucosamine-6-phosphate isomerase, putative; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
  
 
 0.748
EDY80851.1
[F] COG0516 IMP dehydrogenase/GMP reductase.
   
 
 0.743
EDY84066.1
Conserved hypothetical protein TIGR00275; [R] COG2081 Predicted flavoproteins.
  
    0.627
EDY84662.1
[E] COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; Belongs to the HisA/HisF family.
  
    0.623
EDY85163.1
Transporter, major facilitator family, putative; [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
 
 0.623
EDY80587.1
Glycosyltransferase family 28 C-terminal domain; [S] COG5017 Uncharacterized conserved protein.
    
  0.614
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.613
EDY82921.1
CBS domain pair protein; [C] COG1227 Inorganic pyrophosphatase/exopolyphosphatase.
   
 
  0.608
Your Current Organism:
Verrucomicrobiae bacterium DG1235
NCBI taxonomy Id: 382464
Other names: V. bacterium DG1235, Verrucomicrobiae bacterium str. DG1235, Verrucomicrobiae bacterium strain DG1235, Verrucomicrobiales bacterium DG1235
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