STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDY83437.1Phosphotransferase enzyme family, putative; [R] COG2334 Putative homoserine kinase type II (protein kinase fold). (327 aa)    
Predicted Functional Partners:
EDY83365.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.736
EDY81683.1
[E] COG0498 Threonine synthase.
    
 0.594
EDY80986.1
Hypothetical protein; [P] COG0607 Rhodanese-related sulfurtransferase.
  
 
  0.584
EDY83920.1
Homoserine dehydrogenase, NAD binding domain family; [E] COG0460 Homoserine dehydrogenase.
    
 0.568
EDY84449.1
Asparate kinase, monofunctional class; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family.
  
 
 0.525
EDY83813.1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase subfamily; [E] COG2873 O-acetylhomoserine sulfhydrylase.
    
  0.512
EDY84907.1
Aminotransferase, classes I and II superfamily; [E] COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities.
   
 
  0.497
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
  0.492
EDY82859.1
[NT] COG0840 Methyl-accepting chemotaxis protein.
       0.486
EDY84835.1
Hypothetical protein.
       0.486
Your Current Organism:
Verrucomicrobiae bacterium DG1235
NCBI taxonomy Id: 382464
Other names: V. bacterium DG1235, Verrucomicrobiae bacterium str. DG1235, Verrucomicrobiae bacterium strain DG1235, Verrucomicrobiales bacterium DG1235
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