STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDY80735.1Oxidoreductase, FAD/FMN-binding superfamily; [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (314 aa)    
Predicted Functional Partners:
EDY82766.1
[E] COG0069 Glutamate synthase domain 2.
    
 0.852
EDY84130.1
[E] COG0069 Glutamate synthase domain 2.
    
 0.852
EDY83532.1
Fumarate hydratase I, N-terminal region or alpha subunit domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.745
EDY85163.1
Transporter, major facilitator family, putative; [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
  
 
 0.583
EDY80889.1
Aldehyde dehydrogenase (NAD) family protein; [E] COG0506 Proline dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.513
EDY83260.1
acetyl-CoA acetyltransferases subfamily; [I] COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
   
 
 0.498
EDY83877.1
[O] COG0492 Thioredoxin reductase.
  
 
 0.490
EDY83286.1
Fumarylacetoacetate hydrolase family protein; [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
    
 0.489
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.484
EDY80984.1
Nitroreductase family protein; [C] COG0778 Nitroreductase.
  
 
 0.481
Your Current Organism:
Verrucomicrobiae bacterium DG1235
NCBI taxonomy Id: 382464
Other names: V. bacterium DG1235, Verrucomicrobiae bacterium str. DG1235, Verrucomicrobiae bacterium strain DG1235, Verrucomicrobiales bacterium DG1235
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