node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDY81383.1 | EDY81458.1 | VDG1235_1001 | VDG1235_1076 | Preprotein translocase, SecG subunit, putative; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | [U] COG1862 Preprotein translocase subunit YajC. | 0.810 |
EDY81383.1 | pheT | VDG1235_1001 | VDG1235_761 | Preprotein translocase, SecG subunit, putative; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.453 |
EDY81383.1 | secA | VDG1235_1001 | VDG1235_1100 | Preprotein translocase, SecG subunit, putative; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.956 |
EDY81383.1 | secE | VDG1235_1001 | VDG1235_4804 | Preprotein translocase, SecG subunit, putative; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.991 |
EDY81383.1 | secF | VDG1235_1001 | VDG1235_3690 | Preprotein translocase, SecG subunit, putative; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein-export membrane protein SecD, putative; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.991 |
EDY81383.1 | secY | VDG1235_1001 | VDG1235_2768 | Preprotein translocase, SecG subunit, putative; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.978 |
EDY81383.1 | yidC | VDG1235_1001 | VDG1235_3203 | Preprotein translocase, SecG subunit, putative; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 60Kd inner membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.957 |
EDY81458.1 | EDY81383.1 | VDG1235_1076 | VDG1235_1001 | [U] COG1862 Preprotein translocase subunit YajC. | Preprotein translocase, SecG subunit, putative; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.810 |
EDY81458.1 | secA | VDG1235_1076 | VDG1235_1100 | [U] COG1862 Preprotein translocase subunit YajC. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.788 |
EDY81458.1 | secE | VDG1235_1076 | VDG1235_4804 | [U] COG1862 Preprotein translocase subunit YajC. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.852 |
EDY81458.1 | secF | VDG1235_1076 | VDG1235_3690 | [U] COG1862 Preprotein translocase subunit YajC. | Protein-export membrane protein SecD, putative; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.995 |
EDY81458.1 | secY | VDG1235_1076 | VDG1235_2768 | [U] COG1862 Preprotein translocase subunit YajC. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.818 |
EDY81458.1 | yidC | VDG1235_1076 | VDG1235_3203 | [U] COG1862 Preprotein translocase subunit YajC. | 60Kd inner membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.808 |
EDY82766.1 | EDY84130.1 | VDG1235_2389 | VDG1235_3760 | [E] COG0069 Glutamate synthase domain 2. | [E] COG0069 Glutamate synthase domain 2. | 0.999 |
EDY82766.1 | pheT | VDG1235_2389 | VDG1235_761 | [E] COG0069 Glutamate synthase domain 2. | [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.859 |
EDY82766.1 | purL | VDG1235_2389 | VDG1235_4587 | [E] COG0069 Glutamate synthase domain 2. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.930 |
EDY82766.1 | secF | VDG1235_2389 | VDG1235_3690 | [E] COG0069 Glutamate synthase domain 2. | Protein-export membrane protein SecD, putative; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.934 |
EDY84130.1 | EDY82766.1 | VDG1235_3760 | VDG1235_2389 | [E] COG0069 Glutamate synthase domain 2. | [E] COG0069 Glutamate synthase domain 2. | 0.999 |
EDY84130.1 | pheT | VDG1235_3760 | VDG1235_761 | [E] COG0069 Glutamate synthase domain 2. | [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.859 |
EDY84130.1 | purL | VDG1235_3760 | VDG1235_4587 | [E] COG0069 Glutamate synthase domain 2. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.930 |