STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDY84553.1Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (291 aa)    
Predicted Functional Partners:
EDY83004.1
uroporphyrin-III C-methyltransferase domain protein; [H] COG0007 Uroporphyrinogen-III methylase.
 0.999
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
 0.995
EDY82493.1
[H] COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 0.990
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 0.959
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; [H] COG0001 Glutamate-1-semialdehyde aminotransferase.
  
 0.929
EDY81930.1
Aminotransferase, class III superfamily; [H] COG0001 Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.888
EDY81964.1
[H] COG0407 Uroporphyrinogen-III decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
 
 0.744
EDY82200.1
Uroporphyrinogen decarboxylase family; [M] COG3306 Glycosyltransferase involved in LPS biosynthesis; Belongs to the uroporphyrinogen decarboxylase family.
  
 0.693
EDY83340.1
Hypothetical protein; Belongs to the uroporphyrinogen decarboxylase family.
  
 0.693
EDY83965.1
[H] COG0407 Uroporphyrinogen-III decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
  
 0.693
Your Current Organism:
Verrucomicrobiae bacterium DG1235
NCBI taxonomy Id: 382464
Other names: V. bacterium DG1235, Verrucomicrobiae bacterium str. DG1235, Verrucomicrobiae bacterium strain DG1235, Verrucomicrobiales bacterium DG1235
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