STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDY80815.1Hypothetical protein; [O] COG0443 Molecular chaperone. (907 aa)    
Predicted Functional Partners:
htpG
Hsp90 protein; Molecular chaperone. Has ATPase activity.
   
 0.974
grpE
Co-chaperone GrpE, putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of [...]
  
 0.966
EDY84546.1
Hypothetical protein.
  
 0.958
EDY81967.1
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type domain protein; [O] COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family.
  
 0.945
EDY82559.1
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type domain protein; [O] COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family.
  
 0.945
EDY83699.1
[O] COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1.
  
 0.945
EDY83990.1
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type domain protein; [O] COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family.
  
 0.945
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 0.937
EDY84119.1
Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
 
     0.903
EDY81984.1
TonB family C-terminal domain protein; [R] COG0666 FOG: Ankyrin repeat.
   
 0.891
Your Current Organism:
Verrucomicrobiae bacterium DG1235
NCBI taxonomy Id: 382464
Other names: V. bacterium DG1235, Verrucomicrobiae bacterium str. DG1235, Verrucomicrobiae bacterium strain DG1235, Verrucomicrobiales bacterium DG1235
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