STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (346 aa)    
Predicted Functional Partners:
EDY84553.1
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.995
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; [H] COG0001 Glutamate-1-semialdehyde aminotransferase.
 
 0.961
EDY83004.1
uroporphyrin-III C-methyltransferase domain protein; [H] COG0007 Uroporphyrinogen-III methylase.
 
  
 0.951
EDY81930.1
Aminotransferase, class III superfamily; [H] COG0001 Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.918
EDY82493.1
[H] COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
  
 0.864
EDY83484.1
Cytochrome C assembly protein; [R] COG4137 ABC-type uncharacterized transport system, permease component.
 
     0.833
EDY82064.1
AMP-binding enzyme domain protein; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins.
   
 
 0.829
EDY80517.1
Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; [C] COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
   
   0.763
EDY83629.1
ExsB family; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins.
    
 0.751
EDY81789.1
tRNA synthetases class I (E and Q), catalytic domain, putative; [J] COG0008 Glutamyl- and glutaminyl-tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.745
Your Current Organism:
Verrucomicrobiae bacterium DG1235
NCBI taxonomy Id: 382464
Other names: V. bacterium DG1235, Verrucomicrobiae bacterium str. DG1235, Verrucomicrobiae bacterium strain DG1235, Verrucomicrobiales bacterium DG1235
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