Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_0037Exonuclease SbcC; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (1117 aa)    
Predicted Functional Partners:
sbcD-2
Nuclease SbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
 0.980
sbcD
DNA repair exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
 0.946
SPRI_7315
Nuclease SbcCD subunit D; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.946
SPRI_7336
DNA repair exonuclease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.946
sbcD-3
Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
 0.945
SPRI_0036
NurA domain; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.936
SPRI_2687
ATP-dependent DNA helicase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.895
SPRI_0039
ATPase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.859
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.807
SPRI_3842
Serine/threonine protein kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.760
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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