Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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[Homology]
Score
SPRI_0058Putative TraA-like protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (136 aa)    
Predicted Functional Partners:
SPRI_2687
ATP-dependent DNA helicase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.831
SPRI_3978
Type VI secretion protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.732
SPRI_3783
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.623
SPRI_3979
ATP/GTP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.518
SPRI_2087
ATP-dependent DNA helicase RecQ; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.485
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.467
SPRI_0059
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.434
SPRI_6823
DNA-directed RNA polymerase sigma-70 factor; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.424
SPRI_3981
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.405
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.400
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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