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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_0112RNA polymerase subunit sigma-24; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (428 aa)    
Predicted Functional Partners:
SPRI_0113
Dgpfaetke family protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.950
SPRI_3137
Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.792
SPRI_7240
Dgpfaetke family protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.790
SPRI_3920
DGPF domain protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.788
SPRI_0114
AraC family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.479
SPRI_0111
CalU12 protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.449
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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